Current (most recent on top)
Ms.Tanisha Goel (Ph.D. student, Dept. of Physiology, YLL School of Medicine, NUS)
Ms. Tanisha Goel received her M.Sc. degree in Drug Discovery and Development from UCL, London in 2018 and completed her B.Sc. from King’s College, London in 2015. She started her graduate studies in 2020 in the Mathuru lab and is interested in examining the role of Chrna5 in comorbid brain disorders.
Dr. Meg Nathan (Research Fellow, Yale-NUS College)
Dr. Meg Nathan completed her Ph.D. from Monash University Malaysia in 2015. She then did an year’s postdoctoral work in Shriners Pediatric Research Center. She joined the Mathuru lab in 2018, and has been working on the use of a Self-Administration Zebrafish Assay (SAZA) to examine preference to addictive substances like alcohol among genetic mutant lines. She is working on CCSER1 gene (Coiled-Coiled Serine Rich Protein 1), OXTR and OXTRL (oxytocin receptor isoforms in zebrafish).
My primary research interests focus on the neurogenetics underlying addictions and my current project aims to understand the role of the nicotinic receptors (nAChRs) in addiction to substance of abuse. I am focusing on the Chrna3-Chrna5-ChrnB4 cluster as most reported studies have associate mutations in these genes to addiction. I have generated several zebrafish mutant lines with mutations in the cluster of genes implicated in addiction using the Crispr-Cas9 technology and I am characterizing the profile of these mutants by means of molecular biology and analyze their response to nicotine using the behavioral assay established in our lab. I hope the findings of my research will shed some insight to the conundrum of addiction!
Matas Vitkauskas (Yale-NUS College)
Saoirse Lightbourne (Yale-NUS College)
Rytis Kazimieras Jonynas (Yale-NUS College)
Daniela Ferreira Franco Moura (Yale-NUS College)
Rebecca Anne Rubright (Yale-NUS College).
Anjali Pal (Barnard College)
Ms. Wang Qing (Yale-NUS College, Class of 2019)
Capstone project titled “Molecular and behavioural characterisation of a novel CHRNB4 zebrafish mutant”. Winner of the Capstone Life Sciences Award 2019 and Outstanding Poster Award, 2019 SfN Singapore Annual Meeting.
CIPE Summer Research Program.
Sara Haghani (Yale-NUS College)
Sara’s summer work in 2018, together with Maharshee automation was subsequently published in 2019 as an original research article titled ” An Automated Assay System to Study Novel Tank Induced Anxiety” in Frontiers of Behavioral Neuroscience (Front. Behav. Neurosci., 08 August 2019)
Lavvona Mark (Yale-NUS College)
Lavvona worked on generating ABeta-CRY2 transgenic fish with Ms. Caroline Kibat. Caroline pursued this work further to demonstrate the utility of the CRY2 system in for studying the physical damage caused by human amyloid beta aggregates triggered by optogenetic methods. The paper that pooled work from 2 other Yale-NUS labs with Chu Hsien Lim as the co-first author and was published in eLife eLife 2020;9:e52589 DOI: 10.7554/eLife.52589.
Malika Mammadoma (Yale-NUS College)
Toby Limanto (Yale-NUS College)
Mr. Ruey Zhe (Yale-NUS College, CIPE Summer Research Program).
I’m interested in many academic disciplines, particularly life sciences and philosophy. I am fascinated by the evolutionary basis of behaviour, and enjoyed running the behaviour experiments at Professor Ajay’s lab.
Ms. Ignacius Tey (A*STAR Summer Attachment, Research Internship)
Ms. Maharshee Karia (McGill University, Research Internship)
I worked in the lab as an Intern through Summer 2017. My projects were based on analysing and representing social recognition data and social decision-making behaviour collected from various experiments done on fish. This mainly involved writing code in Python, with the aim to be able to extend and automate this kind of analysis technique. With a major in Physiology and Mathematics, at McGill University, Canada, this felt like the best way to implement my studies in a project and it allowed me to explore new aspects of research that I may want to take up in the near future. The internship truly showed me how intricately complementary the seemingly dissimilar fields of Statistics and Biological Sciences are.
Mr. Vishnu K Sajeenth (Imperial College London, Research Internship)
I had the pleasure of doing my Summer 2017 internship at Dr Ajay’s lab. I conducted novel behavioural assays on zebrafish which had various induced deletions within the CHRNA3 and CHRNA5 gene loci. This involved constructing a rig to conduct these assays, crossing the relevant fish and carrying out self-administration assays on them. I also carried out DNA extraction, PCR and gel electrophoresis to confirm their genotype. It does not stop there – the copious amounts of knowledge and learning I took away from this internship simply do not fit in a list; ranging from the workings of a professional laboratory to exposing myself to the complex realm of coding in MatLab. I am currently in third year (2017) of Medical School at Imperial College London and have a deep-rooted passion in scientific research. I aspire to one day contribute to the advancements in and understanding of Neuroscience. All in all, it was truly an enriching experience and an honour to have worked in the ASM lab; bringing me one step closer to my dream.
Ms. Sau Tsoi Yee (Yale-NUS College, Final year Capstone Project)
My academic interest is in how thought and behavior is produced, and how these processes may be manipulated to produce different outputs, be it through the use of drugs, conditioning or genetic mutations. In this lab, I worked on characterising the acute behavioural response of Danio rerio to ethanol and examined the role of the CHRNA5 gene in this response using a behavioural assay. I graduated from Yale-NUS College in May 2017 with a major in Life Sciences and minor in Psychology, and my goal is to become a researcher in Neuroscience.